OxLDL anticorps

N° du produit ABIN7670707

Cet anticorps anti-OxLDL est un anticorps Souris Monoclonal détectant OxLDL dans ELISA (Capture). Adapté pour Humain.

Aperçu rapide pour OxLDL anticorps (ABIN7670707)

Antigène: OxLDL (Oxidized Low Density Lipoprotein (OxLDL))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp OxLDL est non-conjugé

Application: ELISA (Capture)

Clone: 6D11

Détail du produit anti-OxLDL anticorps

Fonction: OxLDL Monoclonal Antibody(Capture)

Purification: Protein A/G Purification

Immunogène: Human OxLDL Native Protein

Isotype: IgG1

Information d'application

Indications d'application: ELISA Capture 2-8 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Sterile PBS , pH 7.4

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C Valid for 1 month or -20°C Valid for 12 months

Date de péremption: 12 months

Détails sur OxLDL

Antigène: OxLDL (Oxidized Low Density Lipoprotein (OxLDL))

Autre désignation: OxLDL

Sujet: Oxidized LDL,Ox LDL,Ox-LDL,Oxidized lDl (Ox-lDl) is a class of modified lDl. In addition to oxidation-modified lDl,modified lDl also includes acetylated lDl directly combined with malondialdehyde (MDA) and 4-hydroxylenic acid (4-HNE). These lDl which are not oxidation-modified but only chemically modified are called derived lDl. Different from derived lDl,Ox-lDl has unique physiological characteristics in the following aspects: (1) Ox-lDl can affect the metabolism of arachidonic acid and inhibit the esterification of cholesterol,but the derived lDl has no such effect,(2) Ox-lDl consumes endogenous antioxidant substances in lDl and reduces vitamin E content in lDl,while MDA-lDl has no such effect,(3) Oxidative modification involves lipid peroxidation,and PUFAs in lDl are oxidized,(4) When oxidized lDl is low in oxidation degree,ApoB degrades,When the oxidation degree is high,ApoB can be repolymerized. Ox-lDl is not metabolized by lDl receptors,and is recognized,bound,and endocytosed into cells by scavorator receptors. The normal cholesterol metabolism pathway is lost,resulting in intracellular lipid deposition and foam-like transformation.